Volume 12.25 | Jul 2

2020-07-02 | 12.25
Cord Blood News by STEMCELL Technologies
Vol. 12.25 – 2 July, 2020

Efficacy and Safety of Umbilical Cord Mesenchymal Stem Cells in Treatment of Cesarean Section Skin Scars: A Randomized Clinical Trial

Ninety primiparous singleton pregnant women undergoing elective cesarean section were randomly allocated to receive placebo, low-dose, or high-dose transdermal hydrogel umbilical cord-MSCs on the surface of the skin incision.
[Stem Cell Research & Therapy]

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Transient Warming Affects Potency of Cryopreserved Cord Blood Units

The warming kinetics of frozen cord blood units was influenced by both working surfaces and ambient working temperature, with cold plates providing better protection than vinyl or metal surfaces.


Effects of Photobiomodulation Combined with MSCs Transplantation on the Repair of Spinal Cord Injury in Rat

Investigators evaluated the therapeutic effect of human umbilical cord MSCs and laser alone or combined on spinal cord injury.
[Journal of Cellular Physiology]


Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosome-Mediated Transfer of MicroRNA-133b Boosts Trophoblast Cell Proliferation, Migration and Invasion in Preeclampsia by Restricting SGK1

Placentas from preeclampsia patients and normal pregnant women were collected. The human umbilical cord-MSCs and their exosomes were obtained and identified.
[Cell Cycle]


Hepcidin Is a Relevant Iron Status Indicator in Infancy: Results from a Randomized Trial of Early vs. Delayed Cord Clamping

Term infants were randomized to delayed or early cord clamping. Iron status was assessed at four and 12 months. In all cases with iron depletion or iron deficiency and 97 randomly selected iron-replete infants, investigators analyzed hepcidin and explored its correlation to the intervention, iron status, and perinatal factors.
[Pediatric Research]


Effect of Conditioned Medium from Human Umbilical Cord-Derived Mesenchymal Stromal Cells on Rejuvenation of Nucleus Pulposus Derived Stem/Progenitor Cells from Degenerated Intervertebral Disc

Scientists analyzed the expression of MSC and nucleus pulposus cell specific surface markers, pluripotency related genes, multilineage potential and cell proliferative capacity of nucleus pulposus- derived stem/progenitor cells from degenerated disc upon incubation with the conditioned medium which was collected from the umbilical cord derived MSCs.
[International Journal of Stem Cells]

The StemSpan™ T Cell Generation Kit is designed to promote differentiation of HSPCs into T cells in stroma- and serum-free culture conditions.

Embryonic Circulating Endothelial Progenitor Cells

The authors review in the literature concerning the features, origin and physiological functions of embryonic and fetal circulating endothelial progenitors.


Hong Kong Universities Rattled by New Security Law

Academics in Hong Kong are facing new worries after the mainland government abruptly imposed a controversial new security law that critics say could infringe on human rights and chill academic freedom.


United Kingdom Plans ‘Office for Talent’ to Smooth Entry for Top Scientists

The UK government plans to set up an “office for talent” to oversee visas and make it easier to attract top scientists after Brexit, according to an R&D road map.


Amidst Uncertainty, Flexibility Is Key in Higher Ed, Faculty Say

Life sciences professors and other staff make contingency plans for more coronavirus-related disruptions in the coming school year.
[The Scientist]


NIH’s New Sexual-Harassment Rules Are Still Too Weak, Say Critics

On 24 June, the US National Institutes of Health (NIH) described the actions it will take when alerted to reports of unsafe behavior, including restricting scientists from peer-review panels, holding back pending grants and refusing university requests to transfer funding to other institutions in cases where a harasser changes jobs.
[Nature News]



Life Science Innovation Northwest Conference

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Postdoctoral Fellow – Novel Genetic and Epigenetic Regulations

City of Hope – Duarte, California, United States

Postdoctoral Fellow – Pluripotent Stem Cell Biology and Cardiac Disease Modeling

Northwestern University – Chicago, Illinois, United States

Postdoctoral Position – Immune Privilege of the Stem Cell Niche

Columbia University – New York, New York, United States

Research Technician – Cord Blood Preparation

Duke University – Durham, North Carolina, United States

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University of Colorado – Denver, Colorado, United States

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