Volume 3.12 | Mar 31

     In this issue: Science News | Current Publications | Industry News | Policy News | Events
 
TOP STORY
Features of EBV Reactivation After Reduced Intensity Conditioning Unrelated Umbilical Cord Blood Transplantation
Researchers conclude that patients undergoing reduced intensity conditioning umbilical cord blood transplantation are at risk for EBV reactivation, with the need for close EBV monitoring and the use of preemptive rituximab treatment as some cases may progress to life-threatening lymphoproliferative diseases. [Bone Marrow Transplant]

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CURRENT PUBLICATIONS (Ranked by Impact Factor of the Journal)

Functional Expression of the Extracellular Calcium Sensing Receptor (CaSR) in Equine Umbilical Cord Matrix Size-Sieved Stem Cells
The present study investigates the effects of high external calcium concentration and the calcimimetic NPS R-467, a known calcium-sensing receptor agonist, on growth/proliferation of two equine size-sieved umbilical cord matrix mesenchymal stem cell lines. [PLoS ONE]

Mannitol-Containing Macroporous Calcium Phosphate Cement Encapsulating Human Umbilical Cord Stem Cells
The objective of this study was to develop a self-setting, mannitol-containing calcium phosphate cement encapsulating human umbilical cord mesenchymal stem cells for bone tissue engineering. [J Tissue Eng Regen Med]

Trends of Hematopoietic Stem Cell Transplantation in the Eastern Mediterranean Region, 1984-2007
Hematopoietic stem cell transplantation activity was surveyed in the 9 countries in the WHO Eastern Mediterranean region that are reported to carry out transplants. [Biol Blood Marrow Transplant]

Human CD8 T Cells Generated In Vitro from Hematopoietic Stem Cells Are Functionally Mature
Researchers addressed whether functional CD8 T cells can be generated fully in vitro using human umbilical cord blood hematopoietic stem cells in coculture with OP9-DL1 cells. [BMC Immunol]

The Novel Allele, HLA-B*07:68:02, Identified in a German Cord Blood Donor and Her Father
The novel allele HLA-B*07:68:02 identified in two related individuals of Caucasian origin is described. [Tissue Antigens]

Successful Bone Marrow Transplantation in a Pediatric Patient with Chronic Myeloid Leukemia from a HLA-Identical Sibling Selected by Preimplantation HLA Testing
This report describes preimplantation HLA-genotyping to deliver a matched sibling donor for successful transplantation of a malignant disorder. [Pediatr Blood Cancer]

Incidence, Risk Factors and Outcomes of Bronchiolitis Obliterans After Allogeneic Stem Cell Transplantation
Researchers retrospectively analyzed the incidence of and risk factors for bronchiolitis obliterans in allogeneic stem cell transplantation recipients. [Int J Hematol]

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INDUSTRY NEWS
Major China Regenerative Medicine Company Adopts ThermoGenesis Cord Blood Stem Cell Processing and Storage Technologies
ThermoGenesis Corporation said that Nanshan Memorial Medical Institute will be utilizing its AXP® AutoXpress™ and BioArchive® Systems used to process and store stem cells from cord blood in its two stem cell banks in China. [ThermoGenesis Corporation Press Release]

Newborn Possibilities Fund Awards Grant to Georgia Health Sciences University Foundation to Support Groundbreaking Pediatric Research
The Newborn Possibilities Fund, a grant making program established by Cord Blood Registry, announced it will provide its first-ever grant to the Georgia Health Sciences University Foundation. [Cord Blood Registry Press Release]

Massachusetts Life Sciences Center Board Approves 2011 Accelerator Program Loans for Early-Stage Companies
The Massachusetts Life Sciences Center announced the awarding of $3.75 million in loans to five early-stage life sciences companies. [Massachusetts Life Sciences Center Press Release]

PerkinElmer’s ViaCord® Family Cord Blood Banking Business Announces First and Only Service to Bank Stem Cells Harvested from Umbilical Cord Tissue
PerkinElmer, Inc. announced that its family cord blood banking business, ViaCord®, will now offer expectant parents umbilical cord tissue stem cell banking services. [PerkinElmer, Inc. Press Release]

Cord Blood America Enters Agreement with BlueCross BlueShield of Tennessee, Now Offering Stem Cell Collection Services to their Members
Cord Blood America, Inc. announced it has entered into an agreement with BlueCross BlueShield of Tennessee and is now offering the storage of umbilical cord blood at a discount rate as consistent with its other BCBS licensee contracts. [Cord Blood America, Inc. Press Release]
POLICY NEWS
National Institutes of Health (United States)

Food and Drug Administration (United States)

Center for Biologics Evaluation and Research (United States)

European Medicines Agency (European Union)

Medicines and Healthcare Products Regulatory Agency (United Kingdom)

Therapeutic Goods Administration (Australia)
EVENTS

NEW Discussion Workshop: Stem Cells
May 6, 2011
London, United Kingdom

Visit our events page to see a complete list of events in the cord blood community.

JOB OPPORTUNITIES

Implementation Coordinator – Maternity Leave Contract (STEMSOFT Software Inc.)

Lab Technologist – Human Embryonic and Induced Pluripotent Stem Cells (STEMCELL Technologies)

Supervisor Cell Therapy Laboratory – Cord Blood Bank (The University of Texas MD Anderson Cancer Center)

Supervisor Cell Therapy Lab (The University of Texas MD Anderson Cancer Center)

Cell Therapy Manufacturing Manager (Opexa Therapeutics)

Research Associate (University College London Institute of Child Health)

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