Volume 4.32 | Aug 16

Cord Blood News 4.32 August 16, 2012
     In this issue: Publications | Industry News | Policy News | Events | Jobs
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TOP STORY
Immortalized Functional Endothelial Progenitor Cell Lines from Umbilical Cord Blood for Vascular Tissue Engineering
Investigators present the generation of two clones of SV40 immortalized endothelial progenitor cells from umbilical cord blood. These cells retained most of the functional features of mature endothelial cells and showed no indication of senescence after repeated culture for more than 240 days. [Tissue Eng Part C Methods] Abstract

Atlas of Hematopoietic Colonies from Cord Blood
PUBLICATIONS (Ranked by impact factor of the journal)

Activation of Diverse Signaling Pathways by Ex Vivo Delivery of Multiple Cytokines for Myocardial Repair
Researchers investigated whether simultaneous transgenic overexpression of a select quartet of growth factors activates diverse signaling pathways for mobilization and participation of various stem/progenitor cells for cardiogenesis in the infarcted heart. Conditioned medium from transfected skeletal myoblasts was cytoprotective for cardiomyocytes under anoxia, promoted higher trans-well migration of human umbilical cord vein endothelial cells and in vitro tube formation. [Stem Cells Dev] Abstract

Amniotic Fluid-Derived Stem Cells as a Cell Source for Bone Tissue Engineering
Researchers compared the osteogenic potential of both bone marrow-derived stem cells and amniotic fluid-derived stem cells under distinct culture environments to determine whether the osteogenic differentiation process of both types of stem cells is related to the origin of the cells. [Tissue Eng Part A] Abstract

Comparison of In Vitro Hepatogenic Differentiation Potential between Various Placenta-Derived Stem Cells and Other Adult Stem Cells as an Alternative Source of Functional Hepatocytes
Comparative studies of the potential for hepatogenic differentiation among various mesenchymal stem cells (MSCs) are largely lacking. Therefore, researchers investigated and compared the potential for hepatogenic differentiation of placenta-derived stem cells with bone marrow-derived MSCs, adipose-derived MSCs, and umbilical cord blood-derived MSCs. [Differentiation] Abstract

Evaluation of Unrestricted Somatic Stem Cells as a Feeder Layer to Support Undifferentiated Embryonic Stem Cells
Isolated cord blood unrestricted somatic stem cells (USSCs) derived from various donors were used as a novel, supportive feeder layer for growth of C4mES cells. Complete cellular characterization using immunocytochemical and flow cytometric methods were performed on murine embryonic stem cells (mESCs) and human USSCs. [Mol Reprod Dev] Abstract

Effects of Agitation Speed on the Ex Vivo Expansion of Cord Blood Hematopoietic Stem/Progenitor Cells in Stirred Suspension Culture
Mononuclear cells were cultivated in stirred flasks at different agitation speeds. Data indicated that hematopoietic stem/progenitor cells should be cultured at relatively low agitation speed and for a short-term period when cultured in stirred suspension system. [Artif Cells Blood Substit Immobil Biotechnol] Abstract

Comparison of Mesenchymal Stem Cells Derived from Fat, Bone Marrow, Wharton’s Jelly, and Umbilical Cord Blood for Treating Spinal Cord Injuries in Dogs
Scientists isolated the mesenchymal stem cells (MSCs) derived from fat, bone marrow, Wharton’s jelly and umbilical cord blood positive for MSC markers and negative for hematopoietic cell markers. Their effects on the regeneration of injured canine spinal cords were compared. [J Vet Med Sci] Abstract

Complimentary Wallchart: Human Hematopoietic Progenitors. Request Your Copy Today.

INDUSTRY NEWS

China Cord Blood Corporation and Cordlife Group Limited Foster Closer Alliance Across Asia
China Cord Blood Corporation and Cordlife Group Limited are fostering a close strategic partnership to offer umbilical cord blood storage services for expectant parents across Asia. [China Cord Blood Corporation] Press Release

Insception and Lifebank Announce Agreement
Insception Biosciences Inc. and Lifebank Corp. announced that they have entered into a support agreement, pursuant to which Insception has agreed to offer to acquire all of the issued and outstanding common shares in the capital of Lifebank. [Lifebank Corp.] Press Release

Cells for Life Cord Blood Institute Demonstrates Commitment and Dedication to the Highest Quality Standards by Earning FACT Accreditation
By demonstrating compliance with the NETCORD-FACT International Standards, Cells for Life Cord Blood Institute, Inc. has earned FACT Accreditation for Cord Blood Collection, Processing, and Release for Administration Related Allogeneic and Autologous Donations. [Cells for Life Cord Blood Institute, Inc.]
Press Release

Stem Cell Society Singapore Symposium 2012: Stem Cell Based Therapy

POLICY NEWS

National Institutes of Health (United States)

Food and Drug Administration (United States)

Center for Biologics Evaluation and Research (United States)

European Medicines Agency (European Union)

Medicines and Healthcare Products Regulatory Agency (United Kingdom)

Therapeutic Goods Administration (Australia)

EVENTS

NEW CellTech 2013
January 22-23, 2013
San Diego, United States

NEW 18th Congress of European Hematology Association (EHA)
June 13-16, 2013
Stockholm, Sweden

Visit
our events page to see a complete list of events in the cord blood community.

JOB OPPORTUNITIES

Scientist – Mesenchymal Cell Research (STEMCELL Technologies, Inc.)

Research Technologist – Media Development (STEMCELL Technologies, Inc.)

Research Technologist – Research and Development (STEMCELL Technologies, Inc.)

Scientific Communications & Publishing Coordinator (STEMCELL Technologies, Inc.)

Quality Control Operations Coordinator (STEMCELL Technologies, Inc.)

Stem Cell Therapy Scientist (Paramount Recruitment)

Clinical Lab Scientist – Cord Blood (Cardinal Glennon Children’s Medical Center)

Postdoctoral Position – Molecular Biology (Faculty of Informatics, Masaryk University)

Postdoctoral Position – Stem Cell Research (Connecticut Children’s Medical Center, University of Connecticut)

Postdoctoral Fellow – Stem Cell Biology and Developmental Hematopoiesis (Mount Sinai School of Medicine)


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