Preserved In Vivo Reconstitution Ability of PBSCs Cryopreserved for a Decade at -80°C
The authors evaluated viability and functions of PBSCs cryopreserved for more than 10 years. Although recovery rate and viability of CD34+ cells were significantly decreased, myeloid differentiation potential and in vivo reconstitution and self-renewal potential of CD34+ cells in a xenogeneic engraftment assay were maintained for more than 10 years. [Bone Marrow Transplant] Abstract
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ERYTECH Announces Two Positive DSMB Reviews
ERYTECH Pharma announced positive safety reviews after the completion of the first cohort in the company’s US Phase I study with ERY-ASP in acute lymphoblastic leukemia, and following the treatment of the first three patients with ERY-ASP in combination with Folfox in its Phase II study in pancreatic cancer. [ERYTECH Pharma] Press Release